Nosocomial Urinary Tract Infections: Risk Factors, Pathogens, and Prevention Strategies
DOI:
https://doi.org/10.65310/fvf1tq16Keywords:
Urinary Tract Infection, Nosocomial, Pathogen, Prevention, Risk.Abstract
Nosocomial urinary tract infections (NUTI) are one of the most common healthcare-associated infections, particularly in patients with urinary catheters. This article aims to examine the risk factors, causative pathogens, and prevention strategies for NOS based on current literature. The method used was a structured literature review with the PRISMA approach through a search of articles in the Scopus and PubMed databases published between 2020 and 2025. Articles that met the inclusion criteria were analyzed descriptively. The review results showed that the main risk factors included duration of catheter insertion, intensive care unit stay, advanced age, comorbidities, and service factors such as re-catheterization and antibiotic use. The causative pathogens were dominated by Gram-negative bacteria, particularly Escherichia coli, Klebsiella pneumoniae, and Acinetobacter baumannii, with varying distributions across care settings. Effective prevention strategies include limiting catheter use and duration, implementing aseptic technique, close monitoring in high-risk units, and innovation in catheter technology. In conclusion, prevention of nosocomial urinary tract infections requires a comprehensive approach that integrates patient, pathogen, and health care system aspects.
Downloads
References
Ananta, Y., Mustofa, S., Septiani, L., & Busman, H. (2025). Infeksi Saluran Kemih Akibat Penggunaan Kateter pada Pasien Rawat Inap di Rumah Sakit. Medical Profession Journal of Lampung, 15(1), 25-31. https://doi.org/10.53089/medula.v15i1.1436.
APSIC. (2022). APSIC Guide for Prevention of Catheter Associated Urinary Tract Infections (CAUTIs) 2022.. https://apsic-apac.org/wp-content/uploads/2022/06/APSIC-CAUTI-guidelines-2022.pdf.
Darouei, B., Jafari, S., Rostami, S., Nasri, P., Mahjoobipour, H., & Abbasi, S. (2025). Epidemiology, risk factors, and antimicrobial resistance of nosocomial infections in the intensive care unit trauma patients: A cross-sectional study. Journal of Research in Medical Sciences, 30(1), 45. https://doi.org/10.4103/jrms.jrms_469_25.
ECDC (2024). European Centre for Disease Prevention and Control, Surveillance Report: Point Prevalence Survey of Healthcareassociated Infections and Antimicrobial Use in European Acute Care Hospitals.
Erianto, A. V., Asmarawati, T. P., Widodo, A. D. W., Rachman, B. E., Isaridha, I. A., & Arnindita, J. N. (2023). Bacterial Profile and Antibiotic Use in Catheter-Associated Urinary Tract Infection Patients at a Tertiary Referral Hospital in Surabaya, Indonesia. Folia Medica Indonesiana, 59(2), 143-149. https://doi.org/10.20473/fmi.v59i2.39919,
Executive P. (2025). “PRISMA 2020”. https://www.prisma-statement.org/prisma-2020.
Geelhoed, J. P. (2025). Catheter-Associated Urinary Tract Infection (CAUTI). In Principles of Nursing Infection Prevention Control: Enhancing Preparedness: Implementation Across Diverse Fields (Volume 2) (pp. 65-77). Cham: Springer Nature Switzerland. https://doi.org/10.1007/978-3-032-01446-7_5.
Huang, J., & Dong, Y. (2024). Correlation Analysis between Urinary Catheter Indwelling Time and Nosocomial Urinary Tract Infection. Archivos Espanoles de Urologia, 77(5), 577-583. https://doi.org/10.56434/j.arch.esp.urol.20247705.78.
Nababan, T. (2020). Pemasangan Kateter Dengan Kejadian Infeksi Saluran Kemih Pada Pasien Di Ruang Rawat Inap. Jurnal Keperawatan Priority, 3(2), 23-30. https://doi.org/10.34012/jukep.v3i2.961.
Nasution, D., Nababan, D., Sitorus, M. E. J., Manurung, K., & Tarigan, F. L. (2025). Impact of HICPAC Guideline Adherence on Catheter-Associated Urinary Tract Infection Rates: Evidence from a District Hospital in Indonesia. Contagion: Scientific Periodical Journal of Public Health and Coastal Health, 7(1), 174-185. http://dx.doi.org/10.30829/contagion.v7i1.24065.
Nimer, N. A. (2022). Nosocomial infection and antibiotic-resistant threat in the Middle East. Infection and drug resistance, 631-639. https://doi.org/10.2147/IDR.S351755.
Patel, P. K., Advani, S. D., Kofman, A. D., Lo, E., Maragakis, L. L., Pegues, D. A., ... & Meddings, J. (2023). Strategies to prevent catheter-associated urinary tract infections in acute-care hospitals: 2022 Update. Infection Control & Hospital Epidemiology, 44(8), 1209-1231. https://doi.org/10.1017/ice.2023.137.
Perdana, M. A., Wahyuni, D. D., & Yunita, R. (2023). Characteristics and susceptibility pattern of catheter-associated urinary tract infections (CAUTI) bacteria in Indonesia: A study in a national reference hospital of Sumatra region 2020–2021. Narra J, 3(3), e436. https://doi.org/10.52225/narra.v3i3.436.
Prastiyanto, M. E., Iswara, A., Khairunnisa, A., Sofyantoro, F., Siregar, A. R., Mafiroh, W. U., ... & Putri, W. A. (2024). Prevalence and antimicrobial resistance profiles of multidrug-resistant bacterial isolates from urinary tract infections in Indonesian patients: A cross-sectional study. Clinical Infection in Practice, 22, 100359. https://doi.org/10.1016/j.clinpr.2024.100359,
Putri, A. T., Soleha, T. U., Nareswari, S., & Ramadhian, M. R. (2024). Enterobactericeae Sebagai Bakteri Patogen Infeksi Nosokomial di Rumah Sakit. Medical Profession Journal of Lampung, 14(1), 117-121. https://doi.org/10.53089/medula.v14i1.942.
Rosenthal, V. D., Memish, Z. A., Nicastri, E., Leone, S., & Bearman, G. (2025). Preventing catheter-associated urinary tract infections: A position paper of the International Society for Infectious Diseases, 2024 update. International Journal of Infectious Diseases, 151, 107304. https://doi.org/10.1016/j.ijid.2024.107304.
Rosenthal, V. D., Yin, R., Brown, E. C., Lee, B. H., Rodrigues, C., Myatra, S. N., ... & Jin, Z. (2024). Incidence and risk factors for catheter-associated urinary tract infection in 623 intensive care units throughout 37 Asian, African, Eastern European, Latin American, and Middle Eastern nations: A multinational prospective research of INICC. Infection Control & Hospital Epidemiology, 45(5), 567-575. https://doi.org/10.1017/ice.2023.215.
Shen, L., Fu, T., Huang, L., Sun, H., Wang, Y., Sun, L., ... & Ni, C. (2023). 7295 elderly hospitalized patients with catheter-associated urinary tract infection: a case-control study. BMC Infectious Diseases, 23(1), 825. https://doi.org/10.1186/s12879-023-08711-0.
Tailly, T., MacPhee, R. A., Cadieux, P., Burton, J. P., Dalsin, J., Wattengel, C., ... & Razvi, H. (2021). Evaluation of polyethylene glycol-based antimicrobial coatings on urinary catheters in the prevention of Escherichia coli infections in a rabbit model. Journal of Endourology, 35(1), 116-121. https://doi.org/10.1089/end.2020.0186.
WHO. (2022). Global Report on Infection Prevention and Control, https://www.who.int/publications/i/item/9789240051164.
Yajun, L., Xuan, Z., Juan, T., Rui, T., Zuyan, X., Bingbing, Z., ... & Tao, Z. (2025). Risk factors for catheter-associated urinary tract infection in an intensive care unit: a matched case-control study. BMC Infectious Diseases, 25(1), 1-6. https://doi.org/10.1186/s12879-025-10839-0.
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Nisrina Talida Hasan, Sutarto Sutarto, Nanda Fitri Wardani, Novita Carolia (Author)

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.










